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5-Methyl-Tetrahydrofolate and the S-Adenosylmethionine Cycle in C57BL/6J Mouse Tissues: Gender Differences and Effects of Arylamine N-Acetyltransferase-1 Deletion

Folate catabolism involves cleavage of the C(9)-N(10) bond to form p-aminobenzoylgluamate (PABG) and pterin. PABG is then acetylated by human arylamine N-acetyltransferase 1 (NAT1) before excretion in the urine. Mice null for the murine NAT1 homolog (Nat2) show several phenotypes consistent with alt...

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Detalles Bibliográficos
Autores principales:	Witham, Katey L., Butcher, Neville J., Sugamori, Kim S., Brenneman, Debbie, Grant, Denis M., Minchin, Rodney F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808426/ https://www.ncbi.nlm.nih.gov/pubmed/24205029 http://dx.doi.org/10.1371/journal.pone.0077923

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