Cargando…

Inactivation of human myeloperoxidase by hydrogen peroxide()

Human myeloperoxidase (MPO) uses hydrogen peroxide generated by the oxidative burst of neutrophils to produce an array of antimicrobial oxidants. During this process MPO is irreversibly inactivated. This study focused on the unknown role of hydrogen peroxide in this process. When treated with low co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Paumann-Page, Martina, Furtmüller, Paul G., Hofbauer, Stefan, Paton, Louise N., Obinger, Christian, Kettle, Anthony J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808540/ https://www.ncbi.nlm.nih.gov/pubmed/24035742 http://dx.doi.org/10.1016/j.abb.2013.09.004

Ejemplares similares

The staphylococcal inhibitory protein SPIN binds to human myeloperoxidase with picomolar affinity but only dampens halide oxidation
por: Leitgeb, Urban, et al.
Publicado: (2022)

Molecular evolution of hydrogen peroxide degrading enzymes
por: Zámocký, Marcel, et al.
Publicado: (2012)

Pre-steady-state Kinetics Reveal the Substrate Specificity and Mechanism of Halide Oxidation of Truncated Human Peroxidasin 1
por: Paumann-Page, Martina, et al.
Publicado: (2017)

A myeloperoxidase precursor, pro-myeloperoxidase, is present in human plasma and elevated in cardiovascular disease patients
por: Khalilova, Irada S., et al.
Publicado: (2018)

Structure of human promyeloperoxidase (proMPO) and the role of the propeptide in processing and maturation
por: Grishkovskaya, Irina, et al.
Publicado: (2017)

Hydrogen peroxide‐mediated conversion of coproheme to heme b by HemQ—lessons from the first crystal structure and kinetic studies
por: Hofbauer, Stefan, et al.
Publicado: (2016)

Roles of distal aspartate and arginine of B-class dye-decolorizing peroxidase in heterolytic hydrogen peroxide cleavage
por: Pfanzagl, Vera, et al.
Publicado: (2018)

Chlorite dismutases – a heme enzyme family for use in bioremediation and generation of molecular oxygen
por: Hofbauer, Stefan, et al.
Publicado: (2014)

Peroxidasin protein expression and enzymatic activity in metastatic melanoma cell lines are associated with invasive potential
por: Paumann-Page, Martina, et al.
Publicado: (2021)

The hydrogen bonding network of coproheme in coproheme decarboxylase from Listeria monocytogenes: Effect on structure and catalysis
por: Milazzo, Lisa, et al.
Publicado: (2019)

Myeloperoxidase Modulates Hydrogen Peroxide Mediated Cellular Damage in Murine Macrophages
por: Guo, Chaorui, et al.
Publicado: (2020)

Diffused Intra-Oocyte Hydrogen Peroxide Activates Myeloperoxidase and Deteriorates Oocyte Quality
por: Khan, Sana N., et al.
Publicado: (2015)

Crystal structures and calorimetry reveal catalytically relevant binding mode of coproporphyrin and coproheme in coproporphyrin ferrochelatase
por: Hofbauer, Stefan, et al.
Publicado: (2019)

Understanding molecular enzymology of porphyrin-binding α + β barrel proteins - One fold, multiple functions
por: Hofbauer, Stefan, et al.
Publicado: (2021)

Oxidative Status Imbalance in Patients with Metabolic Syndrome: Role of the Myeloperoxidase/Hydrogen Peroxide Axis
por: da Fonseca, Lucas José Sá, et al.
Publicado: (2014)

Insights into the Active Site of Coproheme Decarboxylase from Listeria monocytogenes
por: Milazzo, Lisa, et al.
Publicado: (2018)

Mechanism of reaction of chlorite with mammalian heme peroxidases
por: Jakopitsch, Christa, et al.
Publicado: (2014)

Actinobacterial Coproheme Decarboxylases Use Histidine as a Distal Base to Promote Compound I Formation
por: Michlits, Hanna, et al.
Publicado: (2020)

Inactivation kinetics of horseradish peroxidase (HRP) by hydrogen peroxide
por: Morales-Urrea, Diego, et al.
Publicado: (2023)

Reaction intermediate rotation during the decarboxylation of coproheme to heme b in C. diphtheriae
por: Sebastiani, Federico, et al.
Publicado: (2021)

Transiently Produced Hypochlorite Is Responsible for the Irreversible Inhibition of Chlorite Dismutase
por: Hofbauer, Stefan, et al.
Publicado: (2014)

Impact of subunit and oligomeric structure on the thermal and conformational stability of chlorite dismutases
por: Hofbauer, Stefan, et al.
Publicado: (2012)

Independent evolution of four heme peroxidase superfamilies
por: Zámocký, Marcel, et al.
Publicado: (2015)

Arresting the Catalytic Arginine in Chlorite Dismutases: Impact on Heme Coordination, Thermal Stability, and Catalysis
por: Schmidt, Daniel, et al.
Publicado: (2021)

Agaricus meleagris pyranose dehydrogenase: Influence of covalent FAD linkage on catalysis and stability
por: Krondorfer, Iris, et al.
Publicado: (2014)

Compound I Formation and Reactivity in Dimeric Chlorite Dismutase: Impact of pH and the Dynamics of the Catalytic Arginine
por: Schmidt, Daniel, et al.
Publicado: (2023)

Review of aerosolized hydrogen peroxide, vaporized hydrogen peroxide, and hydrogen peroxide gas plasma in the decontamination of filtering facepiece respirators
por: Berger, Daniel, et al.
Publicado: (2022)

Posttranslational modification and heme cavity architecture of human eosinophil peroxidase—insights from first crystal structure and biochemical characterization
por: Pfanzagl, Vera, et al.
Publicado: (2023)

Turning points in the evolution of peroxidase–catalase superfamily: molecular phylogeny of hybrid heme peroxidases
por: Zámocký, Marcel, et al.
Publicado: (2014)

Pseudoperoxidase activity, conformational stability, and aggregation propensity of the His98Tyr myoglobin variant: implications for the onset of myoglobinopathy
por: Hofbauer, Stefan, et al.
Publicado: (2021)

Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM
por: Chromikova, Veronika, et al.
Publicado: (2015)

Chemistry and Molecular Dynamics Simulations of Heme b-HemQ and Coproheme-HemQ
por: Hofbauer, Stefan, et al.
Publicado: (2016)

Assessment of Formate Dehydrogenase Stress Stability In vivo using Inactivation by Hydrogen Peroxide
por: Savin, S.S., et al.
Publicado: (2010)

From chlorite dismutase towards HemQ–the role of the proximal H-bonding network in haeme binding
por: Hofbauer, Stefan, et al.
Publicado: (2016)

Spectroscopic evidence of the effect of hydrogen peroxide excess on the coproheme decarboxylase from actinobacterial Corynebacterium diphtheriae
por: Sebastiani, Federico, et al.
Publicado: (2022)

Hydrogen Peroxide in Cholera
por: Moitra, N. C.
Publicado: (1919)

Structure and heme-binding properties of HemQ (chlorite dismutase-like protein) from Listeria monocytogenes
por: Hofbauer, Stefan, et al.
Publicado: (2015)

Inactivating influenza viruses on surfaces using hydrogen peroxide or triethylene glycol at low vapor concentrations
por: Rudnick, Stephen N., et al.
Publicado: (2009)

Peroxide of Hydrogen
Publicado: (1888)

Peroxide of Hydrogen
Publicado: (1885)

Cannot write session to /tmp/vufind_sessions/sess_uqlink7k6rn62vjj3kh5eb1k9n