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Expression of the herpes simplex virus type 1 latency-associated transcripts does not influence latency establishment of virus mutants deficient for neuronal replication

Herpes simplex virus type 1 establishes latency within neurons of the trigeminal ganglion. During latency, viral gene expression is largely restricted to the latency-associated transcripts (LATs), which, whilst not essential for any aspect of latency, function to suppress lytic gene expression and e...

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Detalles Bibliográficos
Autores principales:	Nicoll, M. P., Efstathiou, S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for General Microbiology 2013
Materias:	Animal
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809108/ https://www.ncbi.nlm.nih.gov/pubmed/23907392 http://dx.doi.org/10.1099/vir.0.056176-0

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