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Convergent Evolution of Sodium Ion Selectivity in Metazoan Neuronal Signaling
Ion selectivity of metazoan voltage-gated Na(+) channels is critical for neuronal signaling and has long been attributed to a ring of four conserved amino acids that constitute the ion selectivity filter (SF) at the channel pore. Yet, in addition to channels with a preference for Ca(2+) ions, the ex...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809514/ https://www.ncbi.nlm.nih.gov/pubmed/22854023 http://dx.doi.org/10.1016/j.celrep.2012.06.016 |