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Qualitative modeling identifies IL-11 as a novel regulator in maintaining self-renewal in human pluripotent stem cells

Pluripotency in human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) is regulated by three transcription factors—OCT3/4, SOX2, and NANOG. To fully exploit the therapeutic potential of these cells it is essential to have a good mechanistic understanding of the maintenance of...

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Detalles Bibliográficos
Autores principales:	Peterson, Hedi, Abu Dawud, Raed, Garg, Abhishek, Wang, Ying, Vilo, Jaak, Xenarios, Ioannis, Adjaye, James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809568/ https://www.ncbi.nlm.nih.gov/pubmed/24194720 http://dx.doi.org/10.3389/fphys.2013.00303

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