Crevicular Fluid and Serum Concentrations of Progranulin and High Sensitivity CRP in Chronic Periodontitis and Type 2 Diabetes

Introduction. This study was designed to correlate the serum and gingival crevicular fluid (GCF) levels of progranulin (PGRN) and high sensitivity C-reactive protein (hs CRP) in chronic periodontitis and type 2 diabetes mellitus (DM). Design. PGRN and hs CRP levels were estimated in 3 groups: health...

Descripción completa

Detalles Bibliográficos
Autores principales: Priyanka, N., Kumari, Minal, Kalra, Nitish, Arjun, P., Naik, Savitha B., Pradeep, A. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809747/
https://www.ncbi.nlm.nih.gov/pubmed/24191130
http://dx.doi.org/10.1155/2013/803240
_version_ 1782288717612843008
author Priyanka, N.
Kumari, Minal
Kalra, Nitish
Arjun, P.
Naik, Savitha B.
Pradeep, A. R.
author_facet Priyanka, N.
Kumari, Minal
Kalra, Nitish
Arjun, P.
Naik, Savitha B.
Pradeep, A. R.
author_sort Priyanka, N.
collection PubMed
description Introduction. This study was designed to correlate the serum and gingival crevicular fluid (GCF) levels of progranulin (PGRN) and high sensitivity C-reactive protein (hs CRP) in chronic periodontitis and type 2 diabetes mellitus (DM). Design. PGRN and hs CRP levels were estimated in 3 groups: healthy, chronic periodontitis, and type 2 DM with chronic periodontitis. Results. The mean PGRN and hs CRP concentrations in serum and GCF were the highest for group 3 followed by group 2 and the least in group 1. Conclusion. PGRN and hs CRP may be biomarkers of the inflammatory response in type 2 DM and chronic periodontitis.
format Online
Article
Text
id pubmed-3809747
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-38097472013-11-04 Crevicular Fluid and Serum Concentrations of Progranulin and High Sensitivity CRP in Chronic Periodontitis and Type 2 Diabetes Priyanka, N. Kumari, Minal Kalra, Nitish Arjun, P. Naik, Savitha B. Pradeep, A. R. Dis Markers Clinical Study Introduction. This study was designed to correlate the serum and gingival crevicular fluid (GCF) levels of progranulin (PGRN) and high sensitivity C-reactive protein (hs CRP) in chronic periodontitis and type 2 diabetes mellitus (DM). Design. PGRN and hs CRP levels were estimated in 3 groups: healthy, chronic periodontitis, and type 2 DM with chronic periodontitis. Results. The mean PGRN and hs CRP concentrations in serum and GCF were the highest for group 3 followed by group 2 and the least in group 1. Conclusion. PGRN and hs CRP may be biomarkers of the inflammatory response in type 2 DM and chronic periodontitis. Hindawi Publishing Corporation 2013 2013-09-26 /pmc/articles/PMC3809747/ /pubmed/24191130 http://dx.doi.org/10.1155/2013/803240 Text en Copyright © 2013 N. Priyanka et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Priyanka, N.
Kumari, Minal
Kalra, Nitish
Arjun, P.
Naik, Savitha B.
Pradeep, A. R.
Crevicular Fluid and Serum Concentrations of Progranulin and High Sensitivity CRP in Chronic Periodontitis and Type 2 Diabetes
title Crevicular Fluid and Serum Concentrations of Progranulin and High Sensitivity CRP in Chronic Periodontitis and Type 2 Diabetes
title_full Crevicular Fluid and Serum Concentrations of Progranulin and High Sensitivity CRP in Chronic Periodontitis and Type 2 Diabetes
title_fullStr Crevicular Fluid and Serum Concentrations of Progranulin and High Sensitivity CRP in Chronic Periodontitis and Type 2 Diabetes
title_full_unstemmed Crevicular Fluid and Serum Concentrations of Progranulin and High Sensitivity CRP in Chronic Periodontitis and Type 2 Diabetes
title_short Crevicular Fluid and Serum Concentrations of Progranulin and High Sensitivity CRP in Chronic Periodontitis and Type 2 Diabetes
title_sort crevicular fluid and serum concentrations of progranulin and high sensitivity crp in chronic periodontitis and type 2 diabetes
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809747/
https://www.ncbi.nlm.nih.gov/pubmed/24191130
http://dx.doi.org/10.1155/2013/803240
work_keys_str_mv AT priyankan crevicularfluidandserumconcentrationsofprogranulinandhighsensitivitycrpinchronicperiodontitisandtype2diabetes
AT kumariminal crevicularfluidandserumconcentrationsofprogranulinandhighsensitivitycrpinchronicperiodontitisandtype2diabetes
AT kalranitish crevicularfluidandserumconcentrationsofprogranulinandhighsensitivitycrpinchronicperiodontitisandtype2diabetes
AT arjunp crevicularfluidandserumconcentrationsofprogranulinandhighsensitivitycrpinchronicperiodontitisandtype2diabetes
AT naiksavithab crevicularfluidandserumconcentrationsofprogranulinandhighsensitivitycrpinchronicperiodontitisandtype2diabetes
AT pradeepar crevicularfluidandserumconcentrationsofprogranulinandhighsensitivitycrpinchronicperiodontitisandtype2diabetes

Ejemplares similares