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Osthole Mitigates Progressive IgA Nephropathy by Inhibiting Reactive Oxygen Species Generation and NF-κB/NLRP3 Pathway
Renal reactive oxygen species (ROS) and mononuclear leukocyte infiltration are involved in the progressive stage (exacerbation) of IgA nephropathy (IgAN), which is characterized by glomerular proliferation and renal inflammation. The identification of the mechanism responsible for this critical stag...
Autores principales: | Hua, Kuo-Feng, Yang, Shun-Min, Kao, Tzu-Yang, Chang, Jia-Ming, Chen, Hui-Ling, Tsai, Yung-Jen, Chen, Ann, Yang, Sung-Sen, Chao, Louis Kuoping, Ka, Shuk-Man |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810132/ https://www.ncbi.nlm.nih.gov/pubmed/24204969 http://dx.doi.org/10.1371/journal.pone.0077794 |
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