Gene therapy for cancer through adenovirus vector-mediated expression of the Ad5 early region gene 1A based on loss of IGF2 imprinting

Loss of (genomic) imprinting (LOI) of the insulin-like growth factor 2 gene (IGF2) is a common epigenetic abnormality in many human cancers. IGF2 imprinting is regulated by differentially methylated domains (DMD) in the imprinting control region that is located between IGF2 and H19 on human chromoso...

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Detalles Bibliográficos
Autores principales: PAN, YUQIN, HE, BANGSHUN, LIRONG, ZHANG, NIE, ZHENLIN, CHEN, LIPING, GU, LING, HOFFMAN, ANDREW R., WANG, SHUKUI, HU, JIFAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810216/
https://www.ncbi.nlm.nih.gov/pubmed/23900345
http://dx.doi.org/10.3892/or.2013.2646

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