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The contrasting roles of lamin B1 in cellular aging and human disease

The nuclear lamina underlies the inner nuclear membrane and consists of a proteinaceous meshwork of intermediate filaments: the A- and B-type lamins. Mutations in LMNA (encoding lamin A and C) give rise to a variety of human diseases including muscular dystrophies, cardiomyopathies and the premature...

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Detalles Bibliográficos
Autores principales:	Dreesen, Oliver, Ong, Peh Fern, Chojnowski, Alexandre, Colman, Alan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2013
Materias:	Extra View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810336/ https://www.ncbi.nlm.nih.gov/pubmed/23873483 http://dx.doi.org/10.4161/nucl.25808

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