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A Deficiency of Herp, an Endoplasmic Reticulum Stress Protein, Suppresses Atherosclerosis in ApoE Knockout Mice by Attenuating Inflammatory Responses

Herp was originally identified as an endoplasmic reticulum (ER) stress protein in vascular endothelial cells. ER stress is induced in atherosclerotic lesions, but it is not known whether Herp plays any role in the development of atherosclerosis. To address this question, we generated Herp- and apoli...

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Detalles Bibliográficos
Autores principales: Shinozaki, Shohei, Chiba, Tsuyoshi, Kokame, Koichi, Miyata, Toshiyuki, Kaneko, Eiji, Shimokado, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810372/
https://www.ncbi.nlm.nih.gov/pubmed/24204574
http://dx.doi.org/10.1371/journal.pone.0075249