Targeting the Tumour Vasculature: Exploitation of Low Oxygenation and Sensitivity to NOS Inhibition by Treatment with a Hypoxic Cytotoxin

Many cancer research efforts focus on exploiting genetic-level features that may be targeted for therapy. Tissue-level features of the tumour microenvironment also represent useful therapeutic targets. Here we investigate the presence of low oxygen tension and sensitivity to NOS inhibition of tumour...

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Detalles Bibliográficos
Autores principales: Baker, Jennifer H. E., Kyle, Alastair H., Bartels, Kirsten L., Methot, Stephen P., Flanagan, Erin J., Balbirnie, Andrew, Cran, Jordan D., Minchinton, Andrew I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810379/
https://www.ncbi.nlm.nih.gov/pubmed/24204680
http://dx.doi.org/10.1371/journal.pone.0076832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810379/
https://www.ncbi.nlm.nih.gov/pubmed/24204680
http://dx.doi.org/10.1371/journal.pone.0076832

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