Targeting the Tumour Vasculature: Exploitation of Low Oxygenation and Sensitivity to NOS Inhibition by Treatment with a Hypoxic Cytotoxin

Many cancer research efforts focus on exploiting genetic-level features that may be targeted for therapy. Tissue-level features of the tumour microenvironment also represent useful therapeutic targets. Here we investigate the presence of low oxygen tension and sensitivity to NOS inhibition of tumour...

Descripción completa

Detalles Bibliográficos
Autores principales: Baker, Jennifer H. E., Kyle, Alastair H., Bartels, Kirsten L., Methot, Stephen P., Flanagan, Erin J., Balbirnie, Andrew, Cran, Jordan D., Minchinton, Andrew I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810379/
https://www.ncbi.nlm.nih.gov/pubmed/24204680
http://dx.doi.org/10.1371/journal.pone.0076832

Ejemplares similares

Ejemplares similares