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Zeaxanthin Induces Apoptosis in Human Uveal Melanoma Cells through Bcl-2 Family Proteins and Intrinsic Apoptosis Pathway

The cytotoxic effects of zeaxanthin on two human uveal melanoma cell lines (SP6.5 and C918) and related signaling pathways were studied and compared to effects on normal ocular cells (uveal melanocytes, retinal pigment epithelial cells, and scleral fibroblasts). MTT assay revealed that zeaxanthin re...

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Detalles Bibliográficos
Autores principales:	Bi, Ming-Chao, Rosen, Richard, Zha, Ren-Yuan, McCormick, Steven A., Song, E., Hu, Dan-Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810440/ https://www.ncbi.nlm.nih.gov/pubmed/24223611 http://dx.doi.org/10.1155/2013/205082

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