Cargando…

Association of RXR-Gamma Gene Variants with Familial Combined Hyperlipidemia: Genotype and Haplotype Analysis

Background. Familial combined hyperlipidemia (FCHL), the most common genetic form of hyperlipdemia, is characterized by a strong familial clustering and by premature coronary heart disease. The FCHL locus has been mapped to human chromosome 1q21-q23. This region includes the retinoid X receptor gamm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sentinelli, Federica, Minicocci, Ilenia, Montali, Anna, Nanni, Luisa, Romeo, Stefano, Incani, Michela, Cavallo, M. Gisella, Lenzi, Andrea, Arca, Marcello, Baroni, Marco G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810489/ https://www.ncbi.nlm.nih.gov/pubmed/24222859 http://dx.doi.org/10.1155/2013/517943

Ejemplares similares

Glycated hemoglobin for the diagnosis of diabetes and prediabetes: Diagnostic impact on obese and lean subjects, and phenotypic characterization
por: Incani, Michela, et al.
Publicado: (2015)

Association of FTO Polymorphisms with Early Age of Obesity in Obese Italian Subjects
por: Sentinelli, Federica, et al.
Publicado: (2012)

The Arg282Ser missense mutation in APOA5 gene determines a reduction of triglyceride and LDL-cholesterol in children, together with low serum levels of apolipoprotein A-V
por: Bertoccini, Laura, et al.
Publicado: (2017)

Altered Glucose Homeostasis Is Associated with Increased Serum Apelin Levels in Type 2 Diabetes Mellitus
por: Cavallo, Maria Gisella, et al.
Publicado: (2012)

Prevalence of Type 1 Diabetes Autoantibodies (GADA, IA2, and IAA) in Overweight and Obese Children
por: Cambuli, Valentina M., et al.
Publicado: (2010)

The Interplay between Angiopoietin-Like Proteins and Adipose Tissue: Another Piece of the Relationship between Adiposopathy and Cardiometabolic Diseases?
por: Bini, Simone, et al.
Publicado: (2021)

The G-308A variant of the Tumor Necrosis Factor-α (TNF-α) gene is not associated with obesity, insulin resistance and body fat distribution
por: Romeo, Stefano, et al.
Publicado: (2001)

Lack of effect of apolipoprotein C3 polymorphisms on indices of liver steatosis, lipid profile and insulin resistance in obese Southern Europeans
por: Sentinelli, Federica, et al.
Publicado: (2011)

Clinical Implications of Monogenic Versus Polygenic Hypercholesterolemia: Long‐Term Response to Treatment, Coronary Atherosclerosis Burden, and Cardiovascular Events
por: D’Erasmo, Laura, et al.
Publicado: (2021)

RAR/RXR and PPAR/RXR Signaling in Spinal Cord Injury
por: van Neerven, Sabien, et al.
Publicado: (2007)

Regulation of RXR-RAR Heterodimers by RXR- and RAR-Specific Ligands and Their Combinations
por: le Maire, Albane, et al.
Publicado: (2019)

The Fibrinogen-like Domain of ANGPTL3 Facilitates Lipolysis in 3T3-L1 Cells by Activating the Intracellular Erk Pathway
por: Bini, Simone, et al.
Publicado: (2022)

Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization
por: Scheepstra, Marcel, et al.
Publicado: (2017)

Analysis of RXR/THR and RXR/PPARG2 Heterodimerization by Bioluminescence Resonance Energy Transfer (BRET)
por: Mulero, Miquel, et al.
Publicado: (2013)

Association of ACE2 Polymorphisms and Derived Haplotypes With Obesity and Hyperlipidemia in Female Spanish Adolescents
por: Lumpuy-Castillo, Jairo, et al.
Publicado: (2022)

Neurotensin Gene rs2234762 C>G Variant Associates with Reduced Circulating Pro-NT Levels and Predicts Lower Insulin Resistance in Overweight/Obese Children
por: Sentinelli, Federica, et al.
Publicado: (2023)

Testing for type 1 diabetes autoantibodies in gestational diabetes mellitus (GDM): is it clinically useful?
por: Incani, Michela, et al.
Publicado: (2019)

The COBLL1 C allele is associated with lower serum insulin levels and lower insulin resistance in overweight and obese children
por: Mancina, Rosellina Margherita, et al.
Publicado: (2013)

Deep Resequencing of 9 Candidate Genes Identifies a Role for ARAP1 and IGF2BP2 in Modulating Insulin Secretion Adjusted for Insulin Resistance in Obese Southern Europeans
por: Bailetti, Diego, et al.
Publicado: (2022)

Haplotypes versus genotypes on pedigrees
por: Kirkpatrick, Bonnie B
Publicado: (2011)

Haplotype-Based Genotyping in Polyploids
por: Clevenger, Josh P., et al.
Publicado: (2018)

RXR Ligands Negatively Regulate Thrombosis and Hemostasis
por: Unsworth, Amanda J., et al.
Publicado: (2017)

Effectiveness of clinical scores in predicting coronary artery disease in familial hypercholesterolemia: a coronary computed tomography angiography study
por: Catapano, Federica, et al.
Publicado: (2023)

COVID-19 and diabetes: Is this association driven by the DPP4 receptor? Potential clinical and therapeutic implications
por: Barchetta, Ilaria, et al.
Publicado: (2020)

Efficacy of Long-Term Treatment of Autosomal Recessive Hypercholesterolemia With Lomitapide: A Subanalysis of the Pan-European Lomitapide Study
por: D’Erasmo, Laura, et al.
Publicado: (2022)

Molecular Evolution of Ultraspiracle Protein (USP/RXR) in Insects
por: Hult, Ekaterina F., et al.
Publicado: (2011)

RXRα Regulates the Development of Resident Tissue Macrophages
por: Philpott, Jordan, et al.
Publicado: (2022)

Microsecond MD Simulations to Explore the Structural and Energetic Differences between the Human RXRα-PPARγ vs. RXRα-PPARγ-DNA
por: Azam, Faizul, et al.
Publicado: (2022)

New Insights in the Control of Fat Homeostasis: The Role of Neurotensin
por: Barchetta, Ilaria, et al.
Publicado: (2022)

Granzyme B Expression in Visceral Adipose Tissue Associates With Local Inflammation and Glyco-Metabolic Alterations in Obesity
por: Cimini, Flavia Agata, et al.
Publicado: (2020)

Solution Structures of PPARγ2/RXRα Complexes
por: Osz, Judit, et al.
Publicado: (2012)

Structural mechanism for signal transduction in RXR nuclear receptor heterodimers
por: Kojetin, Douglas J., et al.
Publicado: (2015)

RXR Expression in Marine Gastropods with Different Sensitivity to Imposex Development
por: Giulianelli, Sebastián, et al.
Publicado: (2020)

Cytoplasmic Localization of RXRα Determines Outcome in Breast Cancer
por: Zati zehni, Alaleh, et al.
Publicado: (2021)

Quantitative proteomic study of the plasma reveals acute phase response and LXR/RXR and FXR/RXR activation in the chronic unpredictable mild stress mouse model of depression
por: Yang, Chuangchuang, et al.
Publicado: (2018)

Genotype calling and haplotyping in parent-offspring trios
por: Chen, Wei, et al.
Publicado: (2013)

Phenylketonuria in Portugal: Genotype–phenotype correlations using molecular, biochemical, and haplotypic analyses
por: Ferreira, Filipa, et al.
Publicado: (2021)

Monogenic hyperlipidemias
por: Krasi, Geraldo, et al.
Publicado: (2019)

Hyperlipidemias and Obesity
por: Thiriet, Marc
Publicado: (2019)

Multi-Omics Analysis Reveals Up-Regulation of APR Signaling, LXR/RXR and FXR/RXR Activation Pathways in Holstein Dairy Cows Exposed to High-Altitude Hypoxia
por: Kong, Zhiwei, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_n9f9d3jmrjd2nia4p3puf6omak