Susceptibility to Toxoplasmic Retinochoroiditis Is Associated with Hla Alleles Reported to Be Implicated with Rapid Progression to Aids

Background/aims: The frequency of HLA markers associated with rapid progression to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not toxoplasmic retinochoroiditis (TRC). Methods: 98 AIDS patients (25 with TRC, 43 with anti-T. gondii antibodies but without TCR, and 30 without anti-...

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Autores principales: Demarco, Ana Lúcia G., Rodrigues, Maria de Lourdes V., Figueiredo, José Fernando C., Deghaide, Neifi Hassam S., de Menezes, Marcelo Bezerra, Demarco, Luís A., Fernandes, Ana Paula M., Donadi, Eduardo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2012
Materias:
Other
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810704/
https://www.ncbi.nlm.nih.gov/pubmed/23089920
http://dx.doi.org/10.3233/DMA-2012-00935
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author Demarco, Ana Lúcia G.
Rodrigues, Maria de Lourdes V.
Figueiredo, José Fernando C.
Deghaide, Neifi Hassam S.
de Menezes, Marcelo Bezerra
Demarco, Luís A.
Fernandes, Ana Paula M.
Donadi, Eduardo A.
author_facet Demarco, Ana Lúcia G.
Rodrigues, Maria de Lourdes V.
Figueiredo, José Fernando C.
Deghaide, Neifi Hassam S.
de Menezes, Marcelo Bezerra
Demarco, Luís A.
Fernandes, Ana Paula M.
Donadi, Eduardo A.
author_sort Demarco, Ana Lúcia G.
collection PubMed
description Background/aims: The frequency of HLA markers associated with rapid progression to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not toxoplasmic retinochoroiditis (TRC). Methods: 98 AIDS patients (25 with TRC, 43 with anti-T. gondii antibodies but without TCR, and 30 without anti-T. gondii antibodies and without TCR) were studied. Results: The HLA-B35 was significantly increased in TRC group (p = 0.0038). Conclusion: The presence of HLA-B35 may simultaneously predispose to progression to AIDS and TRC.
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spelling pubmed-38107042013-12-10 Susceptibility to Toxoplasmic Retinochoroiditis Is Associated with Hla Alleles Reported to Be Implicated with Rapid Progression to Aids Demarco, Ana Lúcia G. Rodrigues, Maria de Lourdes V. Figueiredo, José Fernando C. Deghaide, Neifi Hassam S. de Menezes, Marcelo Bezerra Demarco, Luís A. Fernandes, Ana Paula M. Donadi, Eduardo A. Dis Markers Other Background/aims: The frequency of HLA markers associated with rapid progression to AIDS was evaluated in Brazilian patients with AIDS exhibiting or not toxoplasmic retinochoroiditis (TRC). Methods: 98 AIDS patients (25 with TRC, 43 with anti-T. gondii antibodies but without TCR, and 30 without anti-T. gondii antibodies and without TCR) were studied. Results: The HLA-B35 was significantly increased in TRC group (p = 0.0038). Conclusion: The presence of HLA-B35 may simultaneously predispose to progression to AIDS and TRC. IOS Press 2012 2012-12-05 /pmc/articles/PMC3810704/ /pubmed/23089920 http://dx.doi.org/10.3233/DMA-2012-00935 Text en Copyright © 2012 Hindawi Publishing Corporation.
spellingShingle Other
Demarco, Ana Lúcia G.
Rodrigues, Maria de Lourdes V.
Figueiredo, José Fernando C.
Deghaide, Neifi Hassam S.
de Menezes, Marcelo Bezerra
Demarco, Luís A.
Fernandes, Ana Paula M.
Donadi, Eduardo A.
Susceptibility to Toxoplasmic Retinochoroiditis Is Associated with Hla Alleles Reported to Be Implicated with Rapid Progression to Aids
title Susceptibility to Toxoplasmic Retinochoroiditis Is Associated with Hla Alleles Reported to Be Implicated with Rapid Progression to Aids
title_full Susceptibility to Toxoplasmic Retinochoroiditis Is Associated with Hla Alleles Reported to Be Implicated with Rapid Progression to Aids
title_fullStr Susceptibility to Toxoplasmic Retinochoroiditis Is Associated with Hla Alleles Reported to Be Implicated with Rapid Progression to Aids
title_full_unstemmed Susceptibility to Toxoplasmic Retinochoroiditis Is Associated with Hla Alleles Reported to Be Implicated with Rapid Progression to Aids
title_short Susceptibility to Toxoplasmic Retinochoroiditis Is Associated with Hla Alleles Reported to Be Implicated with Rapid Progression to Aids
title_sort susceptibility to toxoplasmic retinochoroiditis is associated with hla alleles reported to be implicated with rapid progression to aids
topic Other
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810704/
https://www.ncbi.nlm.nih.gov/pubmed/23089920
http://dx.doi.org/10.3233/DMA-2012-00935
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