Safe Pseudovirus-based Assay for Neutralization Antibodies against Influenza A(H7N9) Virus

Serologic studies are urgently needed to assist in understanding an outbreak of influenza A(H7N9) virus. However, a biosafety level 3 laboratory is required for conventional serologic assays with live lethal virus. We describe a safe pseudovirus–based neutralization assay with preliminary assessment...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiu, Chao, Huang, Yang, Zhang, Anli, Tian, Di, Wan, Yanmin, Zhang, Xiaoling, Zhang, Wanju, Zhang, Zhiyong, Yuan, Zhenghong, Hu, Yunwen, Zhang, Xiaoyan, Xu, Jianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2013
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810762/
https://www.ncbi.nlm.nih.gov/pubmed/24047684
http://dx.doi.org/10.3201/eid1910.130728
Descripción
Sumario:Serologic studies are urgently needed to assist in understanding an outbreak of influenza A(H7N9) virus. However, a biosafety level 3 laboratory is required for conventional serologic assays with live lethal virus. We describe a safe pseudovirus–based neutralization assay with preliminary assessment using subtype H7N9–infected samples and controls.

Ejemplares similares