Rapid Cross-Metathesis for Reversible Protein Modifications via Chemical Access to Se-Allyl-selenocysteine in Proteins

[Image: see text] Cross-metathesis (CM) has recently emerged as a viable strategy for protein modification. Here, efficient protein CM has been demonstrated through biomimetic chemical access to Se-allyl-selenocysteine (Seac), a metathesis-reactive amino acid substrate, via dehydroalanine. On-protei...

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Detalles Bibliográficos
Autores principales: Lin, Yuya A., Boutureira, Omar, Lercher, Lukas, Bhushan, Bhaskar, Paton, Robert S., Davis, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810893/
https://www.ncbi.nlm.nih.gov/pubmed/23889088
http://dx.doi.org/10.1021/ja403191g

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