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Mutagenesis Mapping of the Protein-Protein Interaction Underlying FusB-Type Fusidic Acid Resistance

FusB-type proteins represent the predominant mechanism of resistance to fusidic acid in staphylococci and act by binding to and modulating the function of the drug target (elongation factor G [EF-G]). To gain further insight into this antibiotic resistance mechanism, we sought to identify residues i...

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Detalles Bibliográficos
Autores principales:	Cox, Georgina, Edwards, Thomas A., O'Neill, Alex J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2013
Materias:	Mechanisms of Resistance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811445/ https://www.ncbi.nlm.nih.gov/pubmed/23836182 http://dx.doi.org/10.1128/AAC.00198-13

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