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Metformin Attenuates the Exacerbation of the Allergic Eosinophilic Inflammation in High Fat-Diet-Induced Obesity in Mice
A positive relationship between obesity and asthma has been well documented. The AMP-activated protein kinase (AMPK) activator metformin reverses obesity-associated insulin resistance (IR) and inhibits different types of inflammatory responses. This study aimed to evaluate the effects of metformin o...
Autores principales: | Calixto, Marina Ciarallo, Lintomen, Letícia, André, Diana Majoli, Leiria, Luiz Osório, Ferreira, Danilo, Lellis-Santos, Camilo, Anhê, Gabriel Forato, Bordin, Silvana, Landgraf, Richardt Gama, Antunes, Edson |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811997/ https://www.ncbi.nlm.nih.gov/pubmed/24204674 http://dx.doi.org/10.1371/journal.pone.0076786 |
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