ZASC1 Stimulates HIV-1 Transcription Elongation by Recruiting P-TEFb and TAT to the LTR Promoter

Transcription from the HIV-1 LTR promoter efficiently initiates but rapidly terminates because of a non-processive form of RNA polymerase II. This premature termination is overcome by assembly of an HIV-1 TAT/P-TEFb complex at the transactivation response region (TAR), a structured RNA element encod...

Descripción completa

Detalles Bibliográficos
Autores principales: Bruce, James W., Reddington, Rachel, Mathieu, Elizabeth, Bracken, Megan, Young, John A. T., Ahlquist, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812036/
https://www.ncbi.nlm.nih.gov/pubmed/24204263
http://dx.doi.org/10.1371/journal.ppat.1003712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812036/
https://www.ncbi.nlm.nih.gov/pubmed/24204263
http://dx.doi.org/10.1371/journal.ppat.1003712

Ejemplares similares