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Inactivation of p53 Rescues the Maintenance of High Risk HPV DNA Genomes Deficient in Expression of E6

The human papillomavirus DNA genome undergoes three distinct stages of replication: establishment, maintenance and amplification. We show that the HPV16 E6 protein is required for the maintenance of the HPV16 DNA genome as an extrachromosomal, nuclear plasmid in its natural host cell, the human kera...

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Detalles Bibliográficos
Autores principales:	Lorenz, Laurel D., Rivera Cardona, Jessenia, Lambert, Paul F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812038/ https://www.ncbi.nlm.nih.gov/pubmed/24204267 http://dx.doi.org/10.1371/journal.ppat.1003717

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