Cargando…

Phenobarbital Induces Alterations in the Proteome of Hepatocytes and Mesenchymal Cells of Rat Livers

Preceding studies on the mode of action of non-genotoxic hepatocarcinogens (NGCs) have concentrated on alterations induced in hepatocytes (HCs). A potential role of non-parenchymal liver cells (NPCs) in NGC-driven hepatocarcinogenesis has been largely neglected so far. The aim of this study is to ch...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klepeisz, Philip, Sagmeister, Sandra, Haudek-Prinz, Verena, Pichlbauer, Melanie, Grasl-Kraupp, Bettina, Gerner, Christopher
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812042/ https://www.ncbi.nlm.nih.gov/pubmed/24204595 http://dx.doi.org/10.1371/journal.pone.0076137

Ejemplares similares

Proteome signatures of inflammatory activated primary human peripheral blood mononuclear cells()
por: Haudek-Prinz, Verena J., et al.
Publicado: (2012)

Proteome Analysis Identified the PPARγ Ligand 15d-PGJ2 as a Novel Drug Inhibiting Melanoma Progression and Interfering with Tumor-Stroma Interaction
por: Paulitschke, Verena, et al.
Publicado: (2012)

Proteome profiling in IL-1β and VEGF-activated human umbilical vein endothelial cells delineates the interlink between inflammation and angiogenesis
por: Mohr, Thomas, et al.
Publicado: (2017)

Functional Classification of Cellular Proteome Profiles Support the Identification of Drug Resistance Signatures in Melanoma Cells
por: Paulitschke, Verena, et al.
Publicado: (2013)

Isolation of centrolobular and perilobular hepatocytes after phenobarbital treatment
Publicado: (1975)

Proteomic analysis of hepatic effects of phenobarbital in mice with humanized liver
por: Sprenger, Heike, et al.
Publicado: (2022)

CORRELATED MORPHOMETRIC AND BIOCHEMICAL STUDIES ON THE LIVER CELL : II. Effects of Phenobarbital on Rat Hepatocytes
por: Stäubli, Willy, et al.
Publicado: (1969)

Inherent growth advantage of (pre)malignant hepatocytes associated with nuclear translocation of pro-transforming growth factor α
por: Schausberger, E, et al.
Publicado: (2004)

Mesenchyme-derived factors enhance preneoplastic growth by non-genotoxic carcinogens in rat liver
por: Nejabat, Marzieh, et al.
Publicado: (2017)

New cellular tools reveal complex epithelial–mesenchymal interactions in hepatocarcinogenesis
por: Sagmeister, S, et al.
Publicado: (2008)

Increased protein synthesis by cells exposed to a 1,800-MHz radio-frequency mobile phone electromagnetic field, detected by proteome profiling
por: Gerner, Christopher, et al.
Publicado: (2010)

Autonomous Inhibition of Apoptosis Correlates with Responsiveness of Colon Carcinoma Cell Lines to Ciglitazone
por: Baron, David M., et al.
Publicado: (2014)

A MORPHOMETRIC STUDY OF THE REMOVAL OF PHENOBARBITAL-INDUCED MEMBRANES FROM HEPATOCYTES AFTER CESSATION OF TREATMENT
por: Bolender, Robert P., et al.
Publicado: (1973)

β-Catenin Loss in Hepatocytes Promotes Hepatocellular Cancer after Diethylnitrosamine and Phenobarbital Administration to Mice
por: Awuah, Prince Kwaku, et al.
Publicado: (2012)

Phenobarbital Induces SLC13A5 Expression through Activation of PXR but Not CAR in Human Primary Hepatocytes
por: Li, Zhihui, et al.
Publicado: (2021)

Use of Phenobarbital in Delirium Tremens
por: Fujimoto, Jeffrey, et al.
Publicado: (2017)

Pharmacokinetics and Optimal Dosing of Phenobarbital
por: Shareef, Safiullah, et al.
Publicado: (2018)

Effect of Phenobarbital on Chloramphonicol-Induced Toxicity in Rat Liver and Small Intestine
por: Ahmadizadeh, Massumeh, et al.
Publicado: (2013)

Cell proliferation and apoptosis in normal liver and preneoplastic foci.
por: Schulte-Hermann, R, et al.
Publicado: (1993)

Inhibitory effect of vanadium on rat liver carcinogenesis initiated with diethylnitrosamine and promoted by phenobarbital.
por: Bishayee, A., et al.
Publicado: (1995)

ON THE RELATIONSHIP OF LIVER GLUCOSE-6-PHOSPHATASE TO THE PROLIFERATION OF ENDOPLASMIC RETICULUM IN PHENOBARBITAL INDUCTION
por: Orrenius, Sten, et al.
Publicado: (1966)

Drug-Induced Liver Injury Associated with Noni (Morinda citrifolia) Juice and Phenobarbital
por: Mrzljak, Anna, et al.
Publicado: (2013)

Altered Function and Expression of ABC Transporters at the Blood–Brain Barrier and Increased Brain Distribution of Phenobarbital in Acute Liver Failure Mice
por: Liu, Li, et al.
Publicado: (2018)

Acute liver injury by vinyl chloride: involvement of endoplasmic reticulum in phenobarbital-pretreated rats.
por: Reynolds, E S, et al.
Publicado: (1975)

HETEROGENEITY OF ROUGH-SURFACED LIVER MICROSOMAL MEMBRANES OF ADULT, PHENOBARBITAL-TREATED, AND NEWBORN RATS
por: Dallner, Gustav, et al.
Publicado: (1968)

Inhibitory Effects of S‐Methylcysteine and Cysteine on the Promoting Potential of Sodium Phenobarbital on Rat Liver Carcinogenesis
por: Vijayaraghavan, Meenakshi, et al.
Publicado: (2000)

Species differences in phenobarbital-mediated UGT gene induction in rat and human liver microtissues
por: Plummer, Simon, et al.
Publicado: (2020)

Phenobarbital for Alcohol Withdrawal: Rapid Patient Disposition
por: Richards, John R.
Publicado: (2000)

Interpretation of Controversial Teratogenic Findings of Drugs Such As Phenobarbital
por: Czeizel, Andrew E., et al.
Publicado: (2011)

Comparing the effect of clofibrate and phenobarbital on the newborns with hyperbilirubinemia
por: Hamidi, Majid, et al.
Publicado: (2013)

Suspected Phenobarbital‐Induced Pseudolymphoma in a Dog
por: Lampe, R., et al.
Publicado: (2017)

Suspected phenobarbital-induced fever in a cat
por: Djani, Dylan M, et al.
Publicado: (2019)

Suspected phenobarbital-induced pancytopenia in a cat
por: Lyraki, Maria, et al.
Publicado: (2020)

Ganaxolone versus Phenobarbital for Neonatal Seizure Management
por: Miller, Suzanne L., et al.
Publicado: (2022)

STUDIES ON THE BIOGENESIS OF SMOOTH ENDOPLASMIC RETICULUM MEMBRANES IN HEPATOCYTES OF PHENOBARBITAL-TREATED RATS : II. The Site of Phospholipid Synthesis in the Initial Phase of Membrane Proliferation
por: Higgins, Joan A.
Publicado: (1974)

DEVELOPMENT OF PHENOBARBITAL-SENSITIVE CONTROL MECHANISMS FOR URIDINE DIPHOSPHATE GLUCURONYLTRANSFERASE ACTIVITY IN CHICK EMBRYO LIVER
por: Burchell, Brian, et al.
Publicado: (1972)

Mesenchymal Stem Cell-Derived Hepatocytes for Functional Liver Replacement
por: Christ, Bruno, et al.
Publicado: (2012)

Phenobarbital reduces EEG amplitude and propagation of neonatal seizures but does not alter performance of automated seizure detection
por: Mathieson, Sean R., et al.
Publicado: (2016)

Drug Reactions from Barbital (Veronal) and Phenobarbital (Luminal)
por: Poole, Allan K.
Publicado: (1929)

Effects of vinyl chloride exposures to rats pretreated with phenobarbital.
por: Drew, R T, et al.
Publicado: (1975)

Cannot write session to /tmp/vufind_sessions/sess_rnhvmeri44h47rg9vhrdng4jfb