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Plasmacytoid Dendritic Cells Contribute to Systemic but Not Local Antiviral Responses to HSV Infections
Plasmacytoid dendritic cells (pDC) produce type I interferons (IFN-I) and proinflammatory cytokines in response to viruses; however, their contribution to antiviral immunity in vivo is unclear. In this study, we investigated the impact of pDC depletion on local and systemic antiviral responses to he...
Autores principales: | Swiecki, Melissa, Wang, Yaming, Gilfillan, Susan, Colonna, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812046/ https://www.ncbi.nlm.nih.gov/pubmed/24204273 http://dx.doi.org/10.1371/journal.ppat.1003728 |
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