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An Evolution-Based Approach to De Novo Protein Design and Case Study on Mycobacterium tuberculosis
Computational protein design is a reverse procedure of protein folding and structure prediction, where constructing structures from evolutionarily related proteins has been demonstrated to be the most reliable method for protein 3-dimensional structure prediction. Following this spirit, we developed...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812052/ https://www.ncbi.nlm.nih.gov/pubmed/24204234 http://dx.doi.org/10.1371/journal.pcbi.1003298 |