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Evolutionary Tuning of Protein Expression Levels of a Positively Autoregulated Two-Component System
Cellular adaptation relies on the development of proper regulatory schemes for accurate control of gene expression levels in response to environmental cues. Over- or under-expression can lead to diminished cell fitness due to increased costs or insufficient benefits. Positive autoregulation is a com...
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| Format: | Online Artikel Text |
| Sprache: | English |
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Public Library of Science
2013
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| Online Zugang: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812086/ https://www.ncbi.nlm.nih.gov/pubmed/24204322 http://dx.doi.org/10.1371/journal.pgen.1003927 |