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The Impact of Gene Expression Variation on the Robustness and Evolvability of a Developmental Gene Regulatory Network
Regulatory interactions buffer development against genetic and environmental perturbations, but adaptation requires phenotypes to change. We investigated the relationship between robustness and evolvability within the gene regulatory network underlying development of the larval skeleton in the sea u...
Autores principales: | Garfield, David A., Runcie, Daniel E., Babbitt, Courtney C., Haygood, Ralph, Nielsen, William J., Wray, Gregory A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812118/ https://www.ncbi.nlm.nih.gov/pubmed/24204211 http://dx.doi.org/10.1371/journal.pbio.1001696 |
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