Arabidopsis meiotic crossover hotspots overlap with H2A.Z nucleosomes at gene promoters

PRDM9 directs human meiotic crossover hotspots to intergenic sequence motifs, whereas budding yeast hotspots overlap low nucleosome density regions in gene promoters. To investigate hotspots in plants, which lack PRDM9, we used coalescent analysis of Arabidopsis genetic variation. Crossovers increas...

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Detalles Bibliográficos
Autores principales: Choi, Kyuha, Zhao, Xiaohui, Kelly, Krystyna A., Venn, Oliver, Higgins, James D., Yelina, Nataliya E., Hardcastle, Thomas J., Ziolkowski, Piotr A., Copenhaver, Gregory P., Franklin, F. Chris H., McVean, Gil, Henderson, Ian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812125/
https://www.ncbi.nlm.nih.gov/pubmed/24056716
http://dx.doi.org/10.1038/ng.2766

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