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An Inducible, Isogenic Cancer Cell Line System for Targeting the State of Mismatch Repair Deficiency

The DNA mismatch repair system (MMR) maintains genome stability through recognition and repair of single-base mismatches and small insertion-deletion loops. Inactivation of the MMR pathway causes microsatellite instability and the accumulation of genomic mutations that can cause or contribute to can...

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Detalles Bibliográficos
Autores principales:	Bailis, Julie M., Gordon, Marcia L., Gurgel, Jesse L., Komor, Alexis C., Barton, Jacqueline K., Kirsch, Ilan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812133/ https://www.ncbi.nlm.nih.gov/pubmed/24205301 http://dx.doi.org/10.1371/journal.pone.0078726

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