Cargando…

Humanizing mice for the identification of novel anticancer lipids targeting iNKT cells

The CD1d-dependent presentation of lipid antigens to natural killer T (NKT) cells is an integral part of the innate immune system. However, the development of anticancer therapies based on NKT-cell agonists has had limited success so far. Humanizing mice with respect to the CD1d/NKT antigen presenta...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wen, Xiangshu, Xiong, Ran, Dai, Zhengxi, Kim, Seil, Lawrenczyk, Agnieszka, Yuan, Weiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2013
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812196/ https://www.ncbi.nlm.nih.gov/pubmed/24179706 http://dx.doi.org/10.4161/onci.25475

Ejemplares similares

Exploring the Therapeutic Potentials of iNKT Cells for Anti-HBV Treatment
por: Lawrenczyk, Agnieszka, et al.
Publicado: (2014)

iNKT Cells and Their Potential Lipid Ligands during Viral Infection
por: Opasawatchai, Anunya, et al.
Publicado: (2015)

iNKT and MAIT Cell Alterations in Diabetes
por: Magalhaes, Isabelle, et al.
Publicado: (2015)

The Role of Autophagy in iNKT Cell Development
por: Yang, Guan, et al.
Publicado: (2018)

Recent advances in iNKT cell development
por: Hogquist, Kristin, et al.
Publicado: (2020)

NKT10 cells: a novel iNKT cell subset
por: Wingender, Gerhard, et al.
Publicado: (2015)

Invariant NKT cells: Killers and conspirators against cancer
por: Bassiri, Hamid, et al.
Publicado: (2013)

Regeneration of invariant natural killer T (iNKT) cells: application of iPSC technology for iNKT cell-targeted tumor immunotherapy
por: Aoki, Takahiro, et al.
Publicado: (2023)

NKT cell adjuvants in therapeutic vaccines against hematological cancers
por: Mattarollo, Stephen R., et al.
Publicado: (2013)

How Lipid-Specific T Cells Become Effectors: The Differentiation of iNKT Subsets
por: Wang, Haiguang, et al.
Publicado: (2018)

β-Catenin is required for the differentiation of iNKT2 and iNKT17 cells that augment IL-25-dependent lung inflammation
por: Berga-Bolaños, Rosa, et al.
Publicado: (2015)

Graphene oxide polarizes iNKT cells for production of TGFβ and attenuates inflammation in an iNKT cell-mediated sepsis model
por: Lee, Sung Won, et al.
Publicado: (2018)

Impaired lipid biosynthesis hinders anti-tumor efficacy of intratumoral iNKT cells
por: Fu, Sicheng, et al.
Publicado: (2020)

Exploiting invariant NKT cells to promote T-cell responses to cancer vaccines
por: Hunn, Martin K., et al.
Publicado: (2013)

The iNKT Cell–Macrophage Axis in Homeostasis and Disease
por: Cruz, Mariana S., et al.
Publicado: (2022)

Mrp1 is involved in lipid presentation and iNKT cell activation by Streptococcus pneumoniae
por: Chandra, Shilpi, et al.
Publicado: (2018)

NNKTT120, an anti-iNKT cell monoclonal antibody, produces rapid and sustained iNKT cell depletion in adults with sickle cell disease
por: Field, Joshua J., et al.
Publicado: (2017)

The Ras/MAPK Pathway Is Required for Generation of iNKT Cells
por: Hu, Taishan, et al.
Publicado: (2011)

Developmental Dynamics of Post-Selection Thymic DN iNKT
por: Yassai, Maryam, et al.
Publicado: (2012)

The transcriptional repressor NKAP is required for the development of iNKT cells
por: Thapa, Puspa, et al.
Publicado: (2013)

Histone deacetylase 3 is required for iNKT cell development
por: Thapa, Puspa, et al.
Publicado: (2017)

Enhancing Neuroblastoma Immunotherapies by Engaging iNKT and NK Cells
por: McNerney, Kevin O., et al.
Publicado: (2020)

Alterations of the iNKT cell compartment in brain-injured patients
por: Patinec, Allan, et al.
Publicado: (2019)

The impact of stress on the transcriptomic signature of iNKT1 cells
por: Papadogianni, Georgia, et al.
Publicado: (2021)

Modulation of Tregs and iNKT by Fingolimod in Multiple Sclerosis Patients
por: Ferraro, Diana, et al.
Publicado: (2021)

Human iNKT Cells Modulate Macrophage Survival and Phenotype
por: Loureiro, J. Pedro, et al.
Publicado: (2022)

New insights into iNKT cells and their roles in liver diseases
por: Gu, Xinyu, et al.
Publicado: (2022)

CD8(+) T-cell immunity orchestrated by iNKT cells
por: Qin, Yingyu, et al.
Publicado: (2023)

Cytokine Output of Adipocyte-iNKT Cell Interplay Is Skewed by a Lipid-Rich Microenvironment
por: van Eijkeren, Robert J., et al.
Publicado: (2020)

Colonic Inflammation in Mice Is Improved by Cigarette Smoke through iNKT Cells Recruitment
por: Montbarbon, Muriel, et al.
Publicado: (2013)

A Novel Mouse Model of iNKT Cell-deficiency Generated by CRISPR/Cas9 Reveals a Pathogenic Role of iNKT Cells in Metabolic Disease
por: Ren, Yue, et al.
Publicado: (2017)

Thymic stromal lymphopoietin production in DN32.D3 invariant natural killer T (iNKT) cell line and primary mouse liver iNKT cells
por: Choi, Jun-Pyo, et al.
Publicado: (2021)

Single-cell analysis reveals differences among iNKT cells colonizing peripheral organs and identifies Klf2 as a key gene for iNKT emigration
por: Wang, Jie, et al.
Publicado: (2022)

Regulation of the terminal maturation of iNKT cells by mediator complex subunit 23
por: Xu, Yu, et al.
Publicado: (2018)

α-GalCer and iNKT Cell-Based Cancer Immunotherapy: Realizing the Therapeutic Potentials
por: Zhang, Yingting, et al.
Publicado: (2019)

miR-150 regulates the development of NK and iNKT cells
por: Bezman, Natalie A., et al.
Publicado: (2011)

iNKT Cell Production of GM-CSF Controls Mycobacterium tuberculosis
por: Rothchild, Alissa C., et al.
Publicado: (2014)

An In Silico Approach for Modelling T-Helper Polarizing iNKT Cell Agonists
por: De Spiegeleer, Anton, et al.
Publicado: (2014)

The Pathophysiological Relevance of the iNKT Cell/Mononuclear Phagocyte Crosstalk in Tissues
por: Cortesi, Filippo, et al.
Publicado: (2018)

iNKT: A new avenue for CAR-based cancer immunotherapy
por: Liu, Yilin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qsmuiqg6kil5v0csm5u6vcgm7a