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Humanizing mice for the identification of novel anticancer lipids targeting iNKT cells

The CD1d-dependent presentation of lipid antigens to natural killer T (NKT) cells is an integral part of the innate immune system. However, the development of anticancer therapies based on NKT-cell agonists has had limited success so far. Humanizing mice with respect to the CD1d/NKT antigen presenta...

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Detalles Bibliográficos
Autores principales:	Wen, Xiangshu, Xiong, Ran, Dai, Zhengxi, Kim, Seil, Lawrenczyk, Agnieszka, Yuan, Weiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2013
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812196/ https://www.ncbi.nlm.nih.gov/pubmed/24179706 http://dx.doi.org/10.4161/onci.25475

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