Cargando…
Synthetic Oxoisoaporphine Alkaloids: In Vitro, In Vivo and In Silico Assessment of Antileishmanial Activities
Leishmaniasis is a growing health problem worldwide. As there are certain drawbacks with the drugs currently used to treat human leishmaniasis and resistance to these drugs is emerging, there is a need to develop novel antileishmanial compounds, among which isoquinoline alkaloids are promising candi...
Autores principales: | Sobarzo-Sánchez, Eduardo, Bilbao-Ramos, Pablo, Dea-Ayuela, Maria, González-Díaz, Humberto, Yañez, Matilde, Uriarte, Eugenio, Santana, Lourdes, Martínez-Sernández, Victoria, Bolás-Fernández, Francisco, Ubeira, Florencio M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812281/ https://www.ncbi.nlm.nih.gov/pubmed/24204870 http://dx.doi.org/10.1371/journal.pone.0077560 |
Ejemplares similares
-
Applied Biological and Physicochemical Activity of Isoquinoline Alkaloids: Oxoisoaporphine and Boldine
por: Sobarzo-Sánchez, Eduardo, et al.
Publicado: (2012) -
Study of peptide fingerprints of parasite proteins and drug–DNA interactions with Markov-Mean-Energy invariants of biopolymer molecular-dynamic lattice networks
por: Pérez-Montoto, Lázaro Guillermo, et al.
Publicado: (2009) -
A novel approach to oxoisoaporphine alkaloids via regioselective metalation of alkoxy isoquinolines
por: Melzer, Benedikt C, et al.
Publicado: (2017) -
Oxoisoaporphine as Potent Telomerase Inhibitor
por: Wei, Zu-Zhuang, et al.
Publicado: (2016) -
QSAR for RNases and theoretic–experimental study of molecular diversity on peptide mass fingerprints of a new Leishmania infantum protein
por: González-Díaz, Humberto, et al.
Publicado: (2009)