High glucose activates the alternative ACE2/Ang-(1-7)/Mas and APN/Ang IV/IRAP RAS axes in pancreatic β-cells

The activation of the classical angiotensin (Ang)-converting enzyme (ACE)/Ang II/Ang II type 1 receptor (AT1R) axis of the renin-angiotensin system (RAS) has been associated with islet dysfunction and insulin resistance. Hyperglycaemia, hypertension and obesity, major components of metabolic syndrom...

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Detalles Bibliográficos
Autores principales: HÄRDTNER, CARMEN, MÖRKE, CAROLINE, WALTHER, REINHARD, WOLKE, CARMEN, LENDECKEL, UWE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 201
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812297/
https://www.ncbi.nlm.nih.gov/pubmed/23942780
http://dx.doi.org/ 10.3892/ijmm.2013.1469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812297/
https://www.ncbi.nlm.nih.gov/pubmed/23942780
http://dx.doi.org/ 10.3892/ijmm.2013.1469

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