The abrogation of the HOXB7/PBX2 complex induces apoptosis in melanoma through the miR-221&222-c-FOS pathway

Cutaneous melanoma is the fastest increasing cancer worldwide. Although several molecular abnormalities have been associated with melanoma progression, the underlying mechanisms are still largely unknown and few targeted therapies are under evaluation. Here we show that the HOXB7/PBX2 dimer acts as...

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Detalles Bibliográficos
Autores principales: Errico, M Cristina, Felicetti, Federica, Bottero, Lisabianca, Mattia, Gianfranco, Boe, Alessandra, Felli, Nadia, Petrini, Marina, Bellenghi, Maria, Pandha, Hardev S, Calvaruso, Marco, Tripodo, Claudio, Colombo, Mario P, Morgan, Richard, Carè, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Cancer Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812682/
https://www.ncbi.nlm.nih.gov/pubmed/23400877
http://dx.doi.org/10.1002/ijc.28097

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