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Toward a unified biological hypothesis for the BDNF Val66Met-associated memory deficits in humans: a model of impaired dendritic mRNA trafficking

Brain-derived neurotrophic factor (BDNF) represents promotesa key molecule for the survival and differentiation of specific populations of neurons in the central nervous system. BDNF also regulates plasticity-related processes underlying memory and learning. A common single nucleotide polymorphism (...

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Detalles Bibliográficos
Autores principales: Baj, Gabriele, Carlino, Davide, Gardossi, Lucia, Tongiorgi, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812868/
https://www.ncbi.nlm.nih.gov/pubmed/24198753
http://dx.doi.org/10.3389/fnins.2013.00188