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Site-Specific Stabilization of DNA by a Tethered Major Groove Amine, 7-Aminomethyl-7-deaza-2′-deoxyguanosine

[Image: see text] A cationic 7-aminomethyl-7-deaza-2′-deoxyguanosine (7amG) was incorporated site-specifically into the self-complementary duplex d(G(1)A(2)G(3)A(4)X(5)C(6)G(7)C(8)T(9)C(10)T(11)C(12))(2) (X = 7amG). This construct placed two positively charged amines adjacent to the major groove edg...

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Detalles Bibliográficos
Autores principales:	Szulik, Marta W., Voehler, Markus W., Ganguly, Manjori, Gold, Barry, Stone, Michael P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2013
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812902/ https://www.ncbi.nlm.nih.gov/pubmed/24131376 http://dx.doi.org/10.1021/bi400695r

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