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Golgi-associated RhoBTB3 targets Cyclin E for ubiquitylation and promotes cell cycle progression
Cyclin E regulates the cell cycle transition from G1 to S phase and is degraded before entry into G2 phase. Here we show that RhoBTB3, a Golgi-associated, Rho-related ATPase, regulates the S/G2 transition of the cell cycle by targeting Cyclin E for ubiquitylation. Depletion of RhoBTB3 arrested cells...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812982/ https://www.ncbi.nlm.nih.gov/pubmed/24145166 http://dx.doi.org/10.1083/jcb.201305158 |