Selective COX-2 Inhibitors: A Review of Their Structure-Activity Relationships

Non-steroidal anti-inflammatory drugs (NSAIDs) are the competitive inhibitors of cyclooxygenase (COX), the enzyme which mediates the bioconversion of arachidonic acid to inflammatory prostaglandins (PGs). Their use is associated with the side effects such as gastrointestinal and renal toxicity. The...

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Detalles Bibliográficos
Autores principales: Zarghi, Afshin, Arfaei, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813081/
https://www.ncbi.nlm.nih.gov/pubmed/24250402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813081/
https://www.ncbi.nlm.nih.gov/pubmed/24250402

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