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PEGylation of Octreotide Using an α,β-unsaturated-β′-mono-sulfone Functionalized PEG Reagent

PEGylation is a well-established technique utilized to overcome the problems related to the therapeutic applications of peptides and proteins. Reasons for the PEGylation of these biological macromolecules include reducing immunogenicity, proteolytic degradation and rapid clearance from blood circula...

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Detalles Bibliográficos
Autores principales:	Erfani-Jabarian, Laleh, Dinarvand, Rasoul, Rouini, Mohammad Reza, Atyabi, Fatemeh, Amini, Mohsen, Mohammadhosseini, Negar, Shafiee, Abbas, Foroumadi, Alireza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813111/ https://www.ncbi.nlm.nih.gov/pubmed/24250501

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