5-Fluorouracil Induce the Expression of TLR4 on HCT116 Colorectal Cancer Cell Line Expressing Different Variants of TLR4

Two common single nucleotide polymorphisms (SNPs) of the human TLR4 gene, namely Asp299Gly (D299G) and Thr399Ile (T399I), have been shown to impair the ability of certain individuals to respond properly to TLR4 ligands. 5-Fluorouracil (5-FU) is widely used for the treatment of patients with advanced...

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Detalles Bibliográficos
Autores principales: Davoodi, Homa, Hashemi, Seyed Reza, Seow, Heng Fong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2013
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Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813241/
https://www.ncbi.nlm.nih.gov/pubmed/24250621

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