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Study of Compressibility Properties of Yogurt Powder in Order to Prepare a Complementary Formulation

The aim of the present study was to prepare an oral tablet from liquid yogurt by reforming the physical properties for easy transportation, long-term storage and also as a complementary dairy product in case of nutrient deficiency. The liquid fresh yogurt was lyophilized at -40°C and 0.03 mTor press...

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Autores principales: Moghbel, Abdolhossein, Abbaspour, Hamideh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813281/
https://www.ncbi.nlm.nih.gov/pubmed/24250628
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author Moghbel, Abdolhossein
Abbaspour, Hamideh
author_facet Moghbel, Abdolhossein
Abbaspour, Hamideh
author_sort Moghbel, Abdolhossein
collection PubMed
description The aim of the present study was to prepare an oral tablet from liquid yogurt by reforming the physical properties for easy transportation, long-term storage and also as a complementary dairy product in case of nutrient deficiency. The liquid fresh yogurt was lyophilized at -40°C and 0.03 mTor pressure. The dry powder was homogenized by a 12 mesh size sieve. Some tests such as Carr’s compressibility index, Hausner ratio and the angle of repose were applied to evaluate the flowability of yogurt powder. Study of the deformation of particles during forcing was done by calculation of the elastic recovery index. Carr’s compressibility index percent and Hausner ratio were calculated 15 and 0.94, respectively. The range of repose angle was measured between19-20°. The elastic recovery was obtained up to 60%. Since the hardness of tablets increased by decreasing compression velocity, therefore yogurt powder might have a plastic deformation. The reduction of powder volume due to compression force was about 20% (p < 0.05). Tablets with low fat yogurt showed very good compressibility with 6-12 Strong-Cab (SC) hardness units. Producing a complementary formulated as a tablet from yogurt powder is possible and also maybe therapeutically effective against lactose-intolerance syndrome and preventing antibiotic-associated diarrhea.We suggest that for more authentic confirmation of the type of deformation, it should go through Heckel’s equation analysis, too.
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spelling pubmed-38132812013-11-18 Study of Compressibility Properties of Yogurt Powder in Order to Prepare a Complementary Formulation Moghbel, Abdolhossein Abbaspour, Hamideh Iran J Pharm Res Original Article The aim of the present study was to prepare an oral tablet from liquid yogurt by reforming the physical properties for easy transportation, long-term storage and also as a complementary dairy product in case of nutrient deficiency. The liquid fresh yogurt was lyophilized at -40°C and 0.03 mTor pressure. The dry powder was homogenized by a 12 mesh size sieve. Some tests such as Carr’s compressibility index, Hausner ratio and the angle of repose were applied to evaluate the flowability of yogurt powder. Study of the deformation of particles during forcing was done by calculation of the elastic recovery index. Carr’s compressibility index percent and Hausner ratio were calculated 15 and 0.94, respectively. The range of repose angle was measured between19-20°. The elastic recovery was obtained up to 60%. Since the hardness of tablets increased by decreasing compression velocity, therefore yogurt powder might have a plastic deformation. The reduction of powder volume due to compression force was about 20% (p < 0.05). Tablets with low fat yogurt showed very good compressibility with 6-12 Strong-Cab (SC) hardness units. Producing a complementary formulated as a tablet from yogurt powder is possible and also maybe therapeutically effective against lactose-intolerance syndrome and preventing antibiotic-associated diarrhea.We suggest that for more authentic confirmation of the type of deformation, it should go through Heckel’s equation analysis, too. Shaheed Beheshti University of Medical Sciences 2013 /pmc/articles/PMC3813281/ /pubmed/24250628 Text en © 2013 by School of Pharmacy, Shaheed Beheshti University of Medical Sciences and Health Services This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Moghbel, Abdolhossein
Abbaspour, Hamideh
Study of Compressibility Properties of Yogurt Powder in Order to Prepare a Complementary Formulation
title Study of Compressibility Properties of Yogurt Powder in Order to Prepare a Complementary Formulation
title_full Study of Compressibility Properties of Yogurt Powder in Order to Prepare a Complementary Formulation
title_fullStr Study of Compressibility Properties of Yogurt Powder in Order to Prepare a Complementary Formulation
title_full_unstemmed Study of Compressibility Properties of Yogurt Powder in Order to Prepare a Complementary Formulation
title_short Study of Compressibility Properties of Yogurt Powder in Order to Prepare a Complementary Formulation
title_sort study of compressibility properties of yogurt powder in order to prepare a complementary formulation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813281/
https://www.ncbi.nlm.nih.gov/pubmed/24250628
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