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Structural basis of ion permeation gating in Slo2.1 K(+) channels

The activation gate of ion channels controls the transmembrane flux of permeant ions. In voltage-gated K(+) channels, the aperture formed by the S6 bundle crossing can widen to open or narrow to close the ion permeation pathway, whereas the selectivity filter gates ion flux in cyclic-nucleotide gate...

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Detalles Bibliográficos
Autores principales: Garg, Priyanka, Gardner, Alison, Garg, Vivek, Sanguinetti, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813382/
https://www.ncbi.nlm.nih.gov/pubmed/24166878
http://dx.doi.org/10.1085/jgp.201311064