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Red-Backed Vole Brain Promotes Highly Efficient In Vitro Amplification of Abnormal Prion Protein from Macaque and Human Brains Infected with Variant Creutzfeldt-Jakob Disease Agent
Rapid antemortem tests to detect individuals with transmissible spongiform encephalopathies (TSE) would contribute to public health. We investigated a technique known as protein misfolding cyclic amplification (PMCA) to amplify abnormal prion protein (PrP(TSE)) from highly diluted variant Creutzfeld...
Autores principales: | Nemecek, Julie, Nag, Nabanita, Carlson, Christina M., Schneider, Jay R., Heisey, Dennis M., Johnson, Christopher J., Asher, David M., Gregori, Luisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813480/ https://www.ncbi.nlm.nih.gov/pubmed/24205298 http://dx.doi.org/10.1371/journal.pone.0078710 |
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