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Inhibition of IGF-1R Prevents Ionizing Radiation-Induced Primary Endothelial Cell Senescence
Accelerated senescence is a primary response to cellular stresses including DNA damaging agents (e.g., ionizing radiation) and is widely believed to be caused by continuous proliferative signaling in the presence of cell cycle arrest. Studies of signal transduction pathways leading to accelerated se...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813482/ https://www.ncbi.nlm.nih.gov/pubmed/24205274 http://dx.doi.org/10.1371/journal.pone.0078589 |