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Ectopic Activation of Wnt/β-Catenin Signaling in Lens Fiber Cells Results in Cataract Formation and Aberrant Fiber Cell Differentiation

The Wnt/β-catenin signaling pathway controls many processes during development, including cell proliferation, cell differentiation and tissue homeostasis, and its aberrant regulation has been linked to various pathologies. In this study we investigated the effect of ectopic activation of Wnt/β-caten...

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Detalles Bibliográficos
Autores principales: Antosova, Barbora, Smolikova, Jana, Borkovcova, Romana, Strnad, Hynek, Lachova, Jitka, Machon, Ondrej, Kozmik, Zbynek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813504/
https://www.ncbi.nlm.nih.gov/pubmed/24205179
http://dx.doi.org/10.1371/journal.pone.0078279