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Ectopic Activation of Wnt/β-Catenin Signaling in Lens Fiber Cells Results in Cataract Formation and Aberrant Fiber Cell Differentiation
The Wnt/β-catenin signaling pathway controls many processes during development, including cell proliferation, cell differentiation and tissue homeostasis, and its aberrant regulation has been linked to various pathologies. In this study we investigated the effect of ectopic activation of Wnt/β-caten...
Autores principales: | Antosova, Barbora, Smolikova, Jana, Borkovcova, Romana, Strnad, Hynek, Lachova, Jitka, Machon, Ondrej, Kozmik, Zbynek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813504/ https://www.ncbi.nlm.nih.gov/pubmed/24205179 http://dx.doi.org/10.1371/journal.pone.0078279 |
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