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Administration of Heme Arginate Ameliorates Murine Type 2 Diabetes Independently of Heme Oxygenase Activity
Amelioration of rodent type 2 diabetes by hemin has been linked to increased heme oxygenase (HO) activity, however alternative mechanisms have recently been proposed for its anti-diabetic effect. We sought to determine the anti-diabetic efficacy of heme arginate (HA), a clinically licensed preparati...
Autores principales: | Choudhary, Abhijeet K., Rennie, Jillian, Cairns, Carolynn, Borthwick, Gary, Hughes, Jeremy, Morton, Nicholas M., Kluth, David, Conway, Bryan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813508/ https://www.ncbi.nlm.nih.gov/pubmed/24205160 http://dx.doi.org/10.1371/journal.pone.0078209 |
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