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Latrunculin A Treatment Prevents Abnormal Chromosome Segregation for Successful Development of Cloned Embryos
Somatic cell nuclear transfer to an enucleated oocyte is used for reprogramming somatic cells with the aim of achieving totipotency, but most cloned embryos die in the uterus after transfer. While modifying epigenetic states of cloned embryos can improve their development, the production rate of clo...
Autores principales: | Terashita, Yukari, Yamagata, Kazuo, Tokoro, Mikiko, Itoi, Fumiaki, Wakayama, Sayaka, Li, Chong, Sato, Eimei, Tanemura, Kentaro, Wakayama, Teruhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813513/ https://www.ncbi.nlm.nih.gov/pubmed/24205216 http://dx.doi.org/10.1371/journal.pone.0078380 |
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