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Spectrum of EGFR Gene Copy Number Changes and KRAS Gene Mutation Status in Korean Triple Negative Breast Cancer Patients

Anti-epidermal growth factor receptor (EGFR) therapy has been tried in triple negative breast cancer (TNBC) patients without evaluation of molecular and clinical predictors in several randomized clinical studies. Only fewer than 20% of metastatic TNBCs showed response to anti-EGFR therapy. In order...

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Detalles Bibliográficos
Autores principales: Kim, Yoonjung, Kim, Juwon, Lee, Hy-De, Jeong, Joon, Lee, Woochang, Lee, Kyung-A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813621/
https://www.ncbi.nlm.nih.gov/pubmed/24205362
http://dx.doi.org/10.1371/journal.pone.0079014