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Intrathyroidal parathyroid hyperplasia in tertiary hyperparathyroidism

We report herein a case of intrathyroidal parathyroid hyperplasia in a patient with tertiary hyperparathyroidism. The patient was recommended for parathyroidectomy due to sustained hypercalcemia after kidney transplantation. Preoperative radiologic evaluations showed a benign-looking thyroid mass an...

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Detalles Bibliográficos
Autores principales: Kim, Byung Seup, Ryu, Han Suk, Kang, Kyung Ho, Park, Sung Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813706/
https://www.ncbi.nlm.nih.gov/pubmed/24964443
http://dx.doi.org/10.1093/jscr/rjt034
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author Kim, Byung Seup
Ryu, Han Suk
Kang, Kyung Ho
Park, Sung Jun
author_facet Kim, Byung Seup
Ryu, Han Suk
Kang, Kyung Ho
Park, Sung Jun
author_sort Kim, Byung Seup
collection PubMed
description We report herein a case of intrathyroidal parathyroid hyperplasia in a patient with tertiary hyperparathyroidism. The patient was recommended for parathyroidectomy due to sustained hypercalcemia after kidney transplantation. Preoperative radiologic evaluations showed a benign-looking thyroid mass and three enlarged parathyroid glands. Intraoperative intact parathyroid hormone (iPTH) level and frozen biopsy results indicated a missed parathyroid gland after immediate subtotal parathyroidectomy. Then, a secondary partial resection of thyroid including the thyroid nodule was performed. An excised intrathyroid nodule was diagnosed to be parathyroid hyperplasia by frozen biopsy, and intraoperative iPTH level abruptly decreased. A benign-looking thyroidal mass in patients with secondary or tertiary hyperparathyroidism should be carefully evaluated considering the possibility of an intrathyroidal parathyroid hyperplasia.
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spelling pubmed-38137062013-10-31 Intrathyroidal parathyroid hyperplasia in tertiary hyperparathyroidism Kim, Byung Seup Ryu, Han Suk Kang, Kyung Ho Park, Sung Jun J Surg Case Rep Case Reports We report herein a case of intrathyroidal parathyroid hyperplasia in a patient with tertiary hyperparathyroidism. The patient was recommended for parathyroidectomy due to sustained hypercalcemia after kidney transplantation. Preoperative radiologic evaluations showed a benign-looking thyroid mass and three enlarged parathyroid glands. Intraoperative intact parathyroid hormone (iPTH) level and frozen biopsy results indicated a missed parathyroid gland after immediate subtotal parathyroidectomy. Then, a secondary partial resection of thyroid including the thyroid nodule was performed. An excised intrathyroid nodule was diagnosed to be parathyroid hyperplasia by frozen biopsy, and intraoperative iPTH level abruptly decreased. A benign-looking thyroidal mass in patients with secondary or tertiary hyperparathyroidism should be carefully evaluated considering the possibility of an intrathyroidal parathyroid hyperplasia. Oxford University Press 2013-05 2013-05-08 /pmc/articles/PMC3813706/ /pubmed/24964443 http://dx.doi.org/10.1093/jscr/rjt034 Text en Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author 2013. http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/3.0/), which permits non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com.
spellingShingle Case Reports
Kim, Byung Seup
Ryu, Han Suk
Kang, Kyung Ho
Park, Sung Jun
Intrathyroidal parathyroid hyperplasia in tertiary hyperparathyroidism
title Intrathyroidal parathyroid hyperplasia in tertiary hyperparathyroidism
title_full Intrathyroidal parathyroid hyperplasia in tertiary hyperparathyroidism
title_fullStr Intrathyroidal parathyroid hyperplasia in tertiary hyperparathyroidism
title_full_unstemmed Intrathyroidal parathyroid hyperplasia in tertiary hyperparathyroidism
title_short Intrathyroidal parathyroid hyperplasia in tertiary hyperparathyroidism
title_sort intrathyroidal parathyroid hyperplasia in tertiary hyperparathyroidism
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813706/
https://www.ncbi.nlm.nih.gov/pubmed/24964443
http://dx.doi.org/10.1093/jscr/rjt034
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