A High-Content Small Molecule Screen Identifies Sensitivity of Glioblastoma Stem Cells to Inhibition of Polo-Like Kinase 1

Glioblastoma multiforme (GBM) is the most common primary brain cancer in adults and there are few effective treatments. GBMs contain cells with molecular and cellular characteristics of neural stem cells that drive tumour growth. Here we compare responses of human glioblastoma-derived neural stem (G...

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Detalles Bibliográficos
Autores principales: Danovi, Davide, Folarin, Amos, Gogolok, Sabine, Ender, Christine, Elbatsh, Ahmed M. O., Engström, Pär G., Stricker, Stefan H., Gagrica, Sladjana, Georgian, Ana, Yu, Ding, U, Kin Pong, Harvey, Kevin J., Ferretti, Patrizia, Paddison, Patrick J., Preston, Jane E., Abbott, N. Joan, Bertone, Paul, Smith, Austin, Pollard, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813721/
https://www.ncbi.nlm.nih.gov/pubmed/24204733
http://dx.doi.org/10.1371/journal.pone.0077053

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