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TLR 2 and 4 Responsiveness from Isolated Peripheral Blood Mononuclear Cells from Rats and Humans as Potential Chronic Pain Biomarkers

BACKGROUND: Chronic pain patients have increased peripheral blood mononuclear cell Interkeukin-1β production following TLR2 and TLR4 simulation. Here we have used a human-to-rat and rat-to-human approach to further investigate whether peripheral blood immune responses to TLR agonists might be suitab...

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Detalles Bibliográficos
Autores principales:	Kwok, Yuen H., Tuke, Jonathan, Nicotra, Lauren L., Grace, Peter M., Rolan, Paul E., Hutchinson, Mark R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813723/ https://www.ncbi.nlm.nih.gov/pubmed/24204973 http://dx.doi.org/10.1371/journal.pone.0077799

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